CD19 Mouse anti-Human, Brilliant Violet 421, Clone: HIB19, BD

Catalog No.	Quantity
BDB562440	100 Tests
BDB562441	25 Tests

Catalog No. BDB562440 Supplier BD Biosciences Supplier No. 562440

Description

Mouse Monoclonal Antibody

The HIB19 monoclonal antibody specifically binds to the 95 kDa type I transmembrane CD19 glycoprotein. CD19 is expressed during all stages of B-cell maturation and differentiation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 is a signal transduction molecule that regulates B cell development, activation, proliferation and differentiation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks the binding of clone B43, another CD19-specific monoclonal antibody. The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen. With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Vioet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Host Species: Mouse
Clone: HIB19
Isotype: IgG1, κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD19
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: HIB19
• Conjugate: Brilliant Violet 421
• Description: B4; B-lymphocyte antigen CD19; Leu-12
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Quantity: 100 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ

For Research Use Only.