CD195 Rat anti-Mouse, BB515, Clone: C34-3448, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 565093
The C34-3448 monoclonal antibody specifically binds to CD195 which is also known as, C-C chemokine receptor type 5 (CCR5). CD195 is a seven transmembrane-spanning G-protein-coupled receptor that belongs to the β- chemokine receptor family. CD195 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation. It signals in response to at least three chemokines: CCL3/MIP-1 α , CCL4/MIP-1 β , and CCL5/RANTES. CD195 is expressed on macrophages and some T-lymphocytes.
|Aqueous buffered solution containing ≤0.09% sodium azide|
|Ccr5; chemokine (C-C) receptor 5; C-C CKR-5; CC-CKR-5; CCR-5; AM4-7|
|Mouse CCR5 aa. 9-30|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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