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Description
The C34-3448 antibody reacts with mouse chemokine receptor CD195 (also known as CCR5), a member of the β - chemokine receptor family. CD195 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation. It signals a response to at least three chemokines: RANTES and macrophage inflammatory protein-1 (MIP-1) α and β . In the mouse system, the gene for CD195 has been mapped to chromosome 9. CD195 mRNA is expressed in heart, spleen and liver tissues, and by macrophages and T-lymphocytes. The immunogen used to generate the C34- 3448 hybridoma was a KLH-conjugated peptide consisting of amino acids 9-30 of mouse CD195 (CCR5).
Specifications
Specifications
| Antigen | CD195 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | C34-3448 |
| Concentration | 0.5mg/mL |
| Conjugate | Unconjugated |
| Description | CCR5 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse CCR5 aa. 9-30 |
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