CD196 Rat anti-Mouse, Brilliant Violet 421, Clone: 140706, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564736

Catalog No. BDB564736

Description

The 140706 monoclonal antibody specifically binds to mouse CD196 (CCR6), a CC chemokine receptor that is expressed on B lymphocytes and subsets of T and dendritic cells. The known ligand for CCR6 is CCL20/MIP-3 α , and together they regulate the migration and recruitment of antigen-presenting and immunocompetent cells during inflammatory and immunological responses.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

• Antigen: CD196
• Clone: 140706
• Description: CCR6, BN-1, CKR-L3, DRY6, KY411, GPR-CY4, STRL22
• Format: Affinity purified
• Immunogen: Mouse CCR6-transfected Rat Cell Line
• Quantity: 25 Tests
• Storage Requirements: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Rat
• Isotype: IgG_2a
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine