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  6. CD1c Mouse anti-Human, BB515, Clone: F10/21A3, BD

CD1c Mouse anti-Human, BB515, Clone: F10/21A3, BD

Catalog No. BDB565055 Shop All BD Biosciences Products
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BDB565054 100 Tests
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Catalog No. BDB565055 Supplier BD Biosciences Supplier No. 565055
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Description

Mouse Monoclonal Antibody

The F10/21A3 monoclonal antibody specifically binds to CD1c. The CD1 family of transmembrane glycoproteins are structurally related to the classical major histocompatibility complex (MHC) proteins. CD1c is a type I transmembrane glycoprotein that forms heterodimers with beta-2-microglobulin. CD1c presents lipids and glycolipids of self or microbial origin to T cells. CD1c is expressed by Langerhans cells, dendritic cells, monocytes, cortical thymocytes, T cells, and some B cells.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g. 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1c
Applications Flow Cytometry
Classification Monoclonal
Clone F10/21A3
Conjugate Brilliant Blue 515 (BB515)
Description CD1; R7; M241; BDCA1
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen GM-CSF- and IL-4-activated Human Monocytes
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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