CD1c Mouse anti-Human, BB515, Clone: F10/21A3, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 565055

Catalog No. BDB565055

Description

The F10/21A3 monoclonal antibody specifically binds to CD1c. The CD1 family of transmembrane glycoproteins are structurally related to the classical major histocompatibility complex (MHC) proteins. CD1c is a type I transmembrane glycoprotein that forms heterodimers with beta-2-microglobulin. CD1c presents lipids and glycolipids of self or microbial origin to T cells. CD1c is expressed by Langerhans cells, dendritic cells, monocytes, cortical thymocytes, T cells, and some B cells.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g. 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Specifications

• Antigen: CD1c
• Classification: Monoclonal
• Conjugate: Brilliant Blue 515 (BB515)
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: GM-CSF- and IL-4-activated Human Monocytes
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: F10/21A3
• Description: CD1; R7; M241; BDCA1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.