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Description
The F10/21A3 monoclonal antibody specifically binds to CD1c. The CD1 family of transmembrane glycoproteins are structurally related to the classical major histocompatibility complex (MHC) proteins. CD1c is a type I transmembrane glycoprotein that forms heterodimers with beta-2-microglobulin. CD1c presents lipids and glycolipids of self or microbial origin to T cells. CD1c is expressed by Langerhans cells, dendritic cells, monocytes, cortical thymocytes, T cells, and some B cells.
The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Specifications
Specifications
| Antigen | CD1c |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | F10/21A3 |
| Conjugate | Brilliant Violet 421 |
| Description | CD1; R7; M241; BDCA1 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide |
| Host Species | Mouse |
| Immunogen | GM-CSF- and IL-4-activated Human Monocytes |
| Purification Method | Affinity Purified |
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For Research Use Only.
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