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CD1d Mouse anti-Human, APC, Clone: CD1d42 (also known as 42.1), BD

Catalog No. BDB563505 Shop All BD Biosciences Products
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BDB563505 100 Tests
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Catalog No. BDB563505 Supplier BD Biosciences Supplier No. 563505
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Mouse Monoclonal Antibody

The CD1d42 monoclonal antibody recognizes CD1d. Cell surface CD1d is structurally homologous to Class I MHC molecules. It consists of a glycosylated type I transmembrane α chain (43-49 kDa) that is non-covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 molecules into two groups. Group 1 includes CD1a, CD1b and CD1c molecules; group 2 includes CD1d molecules and their homologs in other species. CD1d is expressed on cortical thymocytes, B cells, dendritic cells, monocytes, and some nonlymphoid cells including intestinal epithelial cells, hepatocytes and keratinocytes. It is not expressed on resting mature T cells. Studies suggest that CD1d participates in lipid antigen presentation to CD1d-restricted NKT cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1d
Applications Flow Cytometry
Classification Monoclonal
Clone CD1d42 (also known as 42.1)
Conjugate APC
Description R3; R3G1; HMC class I antigen-like glycoprotein CD1D
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CD1d Recombinant Protein
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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