MilliporeSigma™ anti-CD1d Clone: WTH-1,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABC959

Catalog No. MABC959MI

Description

Specifically detects CD1d Clone: WTH-1 in Mouse, Rat samples, and it is validated for Activity Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blotting

Antigen-presenting glycoprotein CD1d (UniProt Q63493; also known as CD1D antigen, CD1d1 antigen, T-cell surface glycoprotein CD1d) is encoded by the Cd1d (also known as Cd1d1) gene (Gene ID 25109) in rat species. CD1d is a nonpolymorphic MHC class I-like molecule which presents nonpeptide ligands (e.g. glycolipids) to natrual killer T (NKT) cells. NKT cells are known to have multiple effects on innate and adaptive immune responses and on the development of pathological conditions. In additon to hematopoietic cells, CD1d protein is also reported to be detected in non-lymphatic tissues in rat, such as the exocrine pancreas and Paneth cells. CD1d is initially produced with a signal peptide sequence (a.a. 1-17), the removal of which yields the mature CD1d with a large extracellular region (a.a.18-304), a transmembrane domain (a.a. 305-325), and a short cytoplasmic tail (a.a. 326-336).

Specifications

• Antigen: CD1d
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q63493
• Host Species: Mouse
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Form: Purified

• Applications: Functional Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: WTH-1
• Formulation: Purified mouse monoclonal IgG2aκ antibody in PBS without preservatives.
• Gene Symbols: CD1d, Cd1d1
• Immunogen: Rat CD1d-transduced M12.4.1.C3 cells.
• Quantity: 100 μg
• Research Discipline: Apoptosis, Cancer
• Gene ID (Entrez): NP_058775
• Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
• Isotype: IgG2a κ

For Research Use Only