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MilliporeSigma™ anti-CD1d Clone: WTH-1,

Catalog No. MABC959MI Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
MABC959MI 100 μg Unconjugated
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Catalog No. MABC959MI Supplier MilliporeSigma™ Supplier No. MABC959
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Description

Mouse Monoclonal Antibody

Specifically detects CD1d Clone: WTH-1 in Mouse, Rat samples, and it is validated for Activity Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blotting

Antigen-presenting glycoprotein CD1d (UniProt Q63493; also known as CD1D antigen, CD1d1 antigen, T-cell surface glycoprotein CD1d) is encoded by the Cd1d (also known as Cd1d1) gene (Gene ID 25109) in rat species. CD1d is a nonpolymorphic MHC class I-like molecule which presents nonpeptide ligands (e.g. glycolipids) to natrual killer T (NKT) cells. NKT cells are known to have multiple effects on innate and adaptive immune responses and on the development of pathological conditions. In additon to hematopoietic cells, CD1d protein is also reported to be detected in non-lymphatic tissues in rat, such as the exocrine pancreas and Paneth cells. CD1d is initially produced with a signal peptide sequence (a.a. 1-17), the removal of which yields the mature CD1d with a large extracellular region (a.a.18-304), a transmembrane domain (a.a. 305-325), and a short cytoplasmic tail (a.a. 326-336).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1d
Applications Functional Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone WTH-1
Conjugate Unconjugated
Formulation Purified mouse monoclonal IgG2aκ antibody in PBS without preservatives.
Gene Accession No. Q63493
Gene Symbols CD1d, Cd1d1
Host Species Mouse
Immunogen Rat CD1d-transduced M12.4.1.C3 cells.
Purification Method Protein G purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer
Primary or Secondary Primary
Gene ID (Entrez) NP_058775
Target Species Mouse, Rat
Content And Storage -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Form Purified
Isotype IgG2a κ
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For Research Use Only

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