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CD1d Mouse anti-Rat, PE, Clone: WTH2 (also known as WTH-2), BD

Catalog No. BDB564634 Shop All BD Biosciences Products
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BDB564634 0.1 mg
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Catalog No. BDB564634 Supplier BD Biosciences Supplier No. 564634

Description

Mouse Monoclonal Antibody

The WTH2 monoclonal antibody specifically binds to rat CD1d and crossreacts with mouse CD1d. CD1d is a type I transmembrane glycoprotein that is noncovalently associated with β2-microglobulin. CD1d is expressed on various cell types including subsets of thymocytes, T cells, B cells, monocytes, macrophages, dendritic cells, endothelial cells and epithelial cells. Although structurally similar to MHC Class I antigens, CD1d molecules are rather non-polymorphic and serve to present non-peptide antigens such as endogenous or microbial glycolipids to T lymphocytes (NKT cells). The WTH1 monoclonal antibody reportedly binds to a non-overlapping epitope on rat CD1d and also crossreacts with mouse CD1d when compared with WTH2. Both WTH1 and WTH2 reportedly interfere with antigen recognition by CD1d-restricted T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD1d
Applications Flow Cytometry
Classification Monoclonal
Clone WTH2 (also known as WTH-2)
Concentration 0.2mg/mL
Conjugate PE
Description Cd1d; Antigen-presenting glycoprotein CD1d
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat CD1d Transfected Cell Line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse, Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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