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  6. CD2 Mouse anti-Human, BUV395, Clone: RPA-2.10, BD

CD2 Mouse anti-Human, BUV395, Clone: RPA-2.10, BD

Catalog No. BDB563819 Shop All BD Biosciences Products
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Catalog No. BDB563819 Supplier BD Biosciences Supplier No. 563819
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Description

Mouse Monoclonal Antibody

The RPA-2.10 monoclonal antibody specifically binds to CD2. CD2 is a 50 kDa single-chain transmembrane glycoprotein, also known as LFA-2 or the receptor for sheep erythrocytes. CD2 belongs to the immunoglobulin superfamily of proteins along with its ligand LFA-3, CD58. It is present on about 80-90% of human peripheral blood lymphocytes, greater than 95% of thymocytes, all T lymphocytes that form E-rosettes and a subset of NK cells. CD2 plays a role in T-cell signaling and in lymphocyte adhesion.

The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD2
Applications Flow Cytometry
Classification Monoclonal
Clone RPA-2.10
Conjugate Brilliant Ultraviolet 395
Description LFA-2; Lymphocyte function antigen-2; T11/Leu-5; Rosette receptor
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Phytohemagglutinin-treated Lymphoblast
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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