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CD20 Mouse anti-Human, Alexa Fluor 647, Clone: H1, BD

Catalog No. BDB558054 Shop All BD Biosciences Products
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BDB558054 50 Tests
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Catalog No. BDB558054 Supplier BD Biosciences Supplier No. 558054
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Description

Mouse Monoclonal Antibody

The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD20
Applications Flow Cytometry
Classification Monoclonal
Clone H1
Conjugate Alexa Fluor 647
Description MS4A1; membrane-spanning 4-domains subfamily A member 1; B1; Bp35; LEU-16
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human B lymphoma cell line
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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