Learn More
CD20 Mouse anti-Human, Brilliant Violet 510, Clone: H1, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 563347
Description
The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.
The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon™ BV510 can be excited by the violet laser and detected in the BD Horizon™ V500 (525/50-nm) filter set. BD Horizon™ BV510 conjugates are useful for the detection of dim markers off the violet laser.
Specifications
CD20 | |
Monoclonal | |
Brilliant Violet 510 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human B lymphoma cell line | |
50 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
H1 | |
MS4A1; membrane-spanning 4-domains subfamily A member 1; B1; Bp35; LEU-16 | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG2a κ |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.