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CD20 Mouse anti-Human, PerCP-Cy5.5, Clone: H1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 558021

Catalog No. BDB558021


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Description

Description

The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD20
Monoclonal
PerCP-Cyanine5.5
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
H1
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human B lymphoma cell line
50 Tests
Immunology
Human
IgG2a κ
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