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Description
The MRC OX-104 monoclonal antibody specifically binds to CD200. CD200 is a 40-45 kDa type 1 transmembrane glycoprotein and is also referred to as OX2. CD200 is a member of the immunoglobulin superfamily of proteins. It contains two Ig domains, a single transmembrane region and a short cytoplasmic tail. CD200 is expressed on resting and PMA-activated T- and B-cells, but not on NK cells, monocytes, granulocytes, or platelets. It has been found on a subset of CD34+ progenitor cells. Interaction of CD200 with its receptor on macrophages induces a downregulation of macrophage activity in a variety of tissues, suggesting a regulatory function.
Specifications
Specifications
| Antigen | CD200 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MRC OX-104 |
| Conjugate | PE-Cyanine7 |
| Description | OX-2; MOX1; MOX2 ; My033 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human CD200 Recombinant Protein |
| Purification Method | Affinity Purified |
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