CD201 Rat anti-Human, Alexa Fluor 488, Clone: RCR-252, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 563623

Catalog No. BDB563623

Description

The RCR-252 monoclonal antibody specifically binds to the endothelial cell protein C receptor (EPCR), which is also known as CD201. CD201 is a 25 kDa, type I transmembrane glycoprotein, expressed on endothelial cells in arteries, veins and capillaries. CD201 binds activated protein C, a serine protease that is involved in regulating blood coagulation. EPCR is reportedly expressed on several malignant cell lines. Malignant cell lines that express EPCR can show significant levels of protein C activation and this activation can be inhibited by anti-EPCR antibody

Specifications

• Antigen: CD201
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: EPCR-positive RE-1 Cells
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: RCR-252
• Description: EPCR; Activated protein C receptor; APC receptor; PROCR; centrocyclin
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ