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CD206 Mouse anti-Human, Unlabeled, Clone: 19.2, BD

Catalog No. BDB555953 Shop All BD Biosciences Products
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BDB555953 0.1 mg
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Catalog No. BDB555953 Supplier BD Biosciences Supplier No. 555953
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Description

Mouse Monoclonal Antibody

Reacts with the macrophage mannose receptor (MR), a membrane glycoprotein of approximately 162kDa which binds to glycoconjugates containing mannose, fucose, or N-acetylglucosamine. These carbohydrates are present on the surface of many microorganisms and enable the macrophage to bind to microorganisms through the MR and internalize them during the process of phagocytosis. Mannose receptors are expressed on human macrophages and cultured dendric cells. They are not detected on resting moncytes. Mannose receptor expression is upregulated on PBMC following 3 day incubation with GM-CSF. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD206
Applications Flow Cytometry
Classification Monoclonal
Clone 19.2
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Macrophage mannose receptor
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Placental Macrophage Mannose Receptor
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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