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CD212 Mouse anti-Human, PE, Clone: 2.1E6, BD

Catalog No. BDB556065 Shop All BD Biosciences Products
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BDB556065 100 Tests
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Catalog No. BDB556065 Supplier BD Biosciences Supplier No. 556065
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Description

Mouse Monoclonal Antibody

Reacts with IL-12Rβ1 subunit, one of two subunits of the IL-12Rβ. IL-12R, expressed mainly on T cells or NK cells, is a member of the hemopoietin receptor superfamily and is related to gp130, granulocyte-colony stimulating factor (G-CSF) receptor and leukemia inhibitory factor (LIF). Reports indicate that together, subunits IL-12Rβ1 and IL-12Rβ2 bind IL-12 with high affinity. IL-12 is an immunomodulatory cytokine produced mainly by antigen-presenting cells (APC) and plays a role in promoting Th1-type responses and cell-mediated immunity. It stimulates proliferation of T cells and NK cells, enhances lytic activity of lymphokine-activated killer (LAK) cells and CTL.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD212
Applications Flow Cytometry
Classification Monoclonal
Clone 2.10E+06
Conjugate PE
Description IL-12R beta 1, IL-12 receptor β1 subunit
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen PHA-activated Human PBMC
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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