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CD22 Mouse anti-Human, PE-Cy7, Clone: HIB22, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563941

Catalog No. BDB563941


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Description

Description

The HIB22 monoclonal antibody specifically binds to CD22. CD22 is a 130-140 kDa glycosylated type I integral membrane protein present on the surface of mature B cells. CD22 is expressed in the cytoplasm of virtually all B cells except plasma cells. CD45RO antigen on T cells and CD75 antigen on B cells have been identified as ligands for CD22. CD22 has been reported to participate in B-cell activation and also as an adhesion molecule. Although the immunobiology of this antigen has not been fully elucidated, reports indicate that ligation of CD22 induces constitutive internalization of the molecule followed by complete degradation.

Specifications

Specifications

CD22
HIB22
BL-CAM; Siglec-2; Bgp135; Lyb8; LPAP
Affinity Purified
IgG1, κ
RUO
Primary
Human
Flow Cytometry
PE-Cyanine7
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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