CD220 Mouse anti-Human, Unlabeled, Clone: 3B6/IR, BD

Catalog No.	Quantity
BDB559954	0.1 mg

Catalog No. BDB559954 Supplier BD Biosciences Supplier No. 559954

Description

Mouse Monoclonal Antibody

Reacts with insulin receptor (IR), a glycoprotein composed of two extracellular α-subunits (130 kDa) and two transmembrane β-subunits (95 kDa). It is expressed on human hematopoietic and non-hematopoietic cells, but unlike the insulin-like growth factor receptor (IGF-IR), which is ubiquitous, the insulin receptor is restricted to major target tissues of insulin action. Upon binding insulin, the IR subunits form a heterotetramer of two α and two β subunits resulting in autophosphorylation and activation of the tyrosine kinase activity of the receptor. This ligand-receptor interaction is important in regulating cell metabolism and growth. 3B6/IR monoclonal antibody reacts similarly to anti-human IR α, clone 47-9, an α-subunit antibody.

Specifications

• Antigen: CD220
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: 3B6/IR
• Concentration: 0.5mg/mL
• Conjugate: Unconjugated
• Description: Insulin Receptor, Insulin R
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Quantity: 0.1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C
• Isotype: IgG1 κ