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CD221 Mouse anti-Human, Unlabeled, Clone: 3B7, BD

Catalog No. BDB556000 Shop All BD Biosciences Products
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BDB556000 0.1 mg
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Catalog No. BDB556000 Supplier BD Biosciences Supplier No. 556000

Description

Mouse Monoclonal Antibody

Reacts with human insulin-like growth factor-I (IGF-I) receptor. IGF-I receptor is a glycoprotein complex composed of two extracellular α subunits and two transmembrane β subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several intracellular signaling proteins. IGF-I receptor is structurally and functionally similar to insulin receptor and is expressed on a variety of human hematopoietic and non-hematopoietic cells. 3B7 antibody does not cross react with human insulin receptor; it stimulates IGF-I and IGF-II induced cell growth and activates autophosphorylation of the IGF-I receptor β subunit.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD221
Applications Flow Cytometry
Classification Monoclonal
Clone 3B7
Concentration 0.5mg/mL
Conjugate Unconjugated
Description IGF-I receptor
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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