CD227 Mouse anti-Human, Unlabeled, Clone: HMPV, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555925

Catalog No. BDB555925

Description

Reacts with the core peptide of the MUC1 protein, a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200kDa) and an amino acid composition rich in serine, threonin, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats which function as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This antibody has been shown to react with both normal and malignant epithelia of various tissues including breast and colon.

Specifications

• Antigen: CD227
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: MUC1; CA 15-3; DF3; EMA; Episialin; H23; H23AG; KL-6; MAM6; PEM; PEMT; PUM
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: HMPV
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Human Milk Fat Globule Membranes
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.