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  6. CD23 Mouse anti-Human, Unlabeled, Clone: M-L233, BD

CD23 Mouse anti-Human, Unlabeled, Clone: M-L233, BD

Catalog No. BDB555707 Shop All BD Biosciences Products
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BDB555707 0.1 mg
BDB555708 0.5 mg
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Catalog No. BDB555707 Supplier BD Biosciences Supplier No. 555707

Description

Mouse Monoclonal Antibody

The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., <12kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.

Host Species: Mouse
Clone: M-L233
Isotype: IgG1 κ
Species Reactivity: Human

Immunohistochemistry, Immunohistochemistry (Frozen)

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD23
Applications Flow Cytometry
Classification Monoclonal
Clone M-L233
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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