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CD244.1 Rat anti-Mouse, Unlabeled, Clone: C9.1, BD

Catalog No. BDB552421 Shop All BD Biosciences Products
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BDB552421 0.1 mg
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Catalog No. BDB552421 Supplier BD Biosciences Supplier No. 552421

Description

Rat Monoclonal Antibody

CD244 (also known as 2B4 Antigen) is a member of the CD2 subset of the immunoglobulin superfamily (CD2 IgSF).3,4,5 It is expressed on all natural killer (NK) cells, IL-2–activated NK cells (LAK), and a subset of T lymphocytes which mediate non-MHC–restricted cytotoxicity. The C9.1 antibody reacts with CD244.1, the 2B4 alloantigen which is expressed in most strains tested (A/J, AKR/N, BALB/c, CBA/N, C3H/He, DBA/1, DBA/2, NZB/N, SJL/J, 129/Svj), but not C57BL/6 or C58/J mice. The expression of the CD244.1 alloantigen on B lymphocytes that was originally described, has not been confirmed in later studies. The extracellular domain of CD244 is a ligand for another CD2 IgSF member, CD48.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD244.1
Applications Flow Cytometry
Classification Monoclonal
Clone C9.1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description 2B4 BALB Alloantigen
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse MHC-unrestricted killer hybridoma 7D4
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2b κ
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For Research Use Only.

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