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CD247 Mouse anti-Mouse, Unlabeled, Clone: 1Z3A1, BD

Catalog No. BDB554241 Shop All BD Biosciences Products
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BDB554241 0.1 mg
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Catalog No. BDB554241 Supplier BD Biosciences Supplier No. 554241

Description

Mouse Monoclonal Antibody

The T-cell receptor (TCR), expressed by thymus-derived lymphocytes, is a multicomponent complex responsible for recognizing antigen in the context of MHC molecules. Ti is the antigen-specific binding component of the TCR. On the majority of peripheral T lymphocytes, Ti is present as a disulfide-linked α - β heterodimer. A minor fraction express Ti as a γ- δ heterodimer. The Ti subunits are Ig-like, each containing V and C regions. Ti is noncovalently associated with an invariant set of molecules referred to as the CD3 subunits. CD3 appears early in thymocyte differentiation and remains expressed on all mature T lymphocytes. In the mouse, it consists of five chains: γ, δ , ε (epsilon), ζ (zeta), and p21. The relative masses of the mouse CD3 chains are 21, 28, 26, 32 (dimer), and 21 kDa respectively.

3A1 recognizes an epitope in the C-terminus of mouse CD3 ζ . A synthetic peptide corresponding to the C-terminus of mouse CD3 ζ (BSACDTYDALHMQTLAPR) was used as immunogen. Hybridomas were derived from Balb/c spleen cells x NS-1.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD247
Applications Western Blot
Classification Monoclonal
Clone 1Z3A1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description CD3ζ chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Mouse CD3ζ C-terminus synthetic peptide
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2b
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For Research Use Only.

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