CD25 Mouse anti-Human, BB515, Clone: M-A251, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 565096
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2R α ). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2R β /CD122 and the IL-2R γ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2R α is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
|IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55|
|Baboon, Cynomolgus, Human, Rhesus|
|Aqueous buffered solution containing ≤0.09% sodium azide|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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