CD25 Mouse anti-Human, Brilliant Violet 786, Clone: M-A251, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 563701

Catalog No. BDB563701

Description

The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as the low-affinity interleukin-2 receptor alpha chain subunit (IL-2R α ). CD25 is expressed on regulatory T cells and on activated lymphocytes (T and B) and monocytes. It associates with the IL-2R β /CD122 and the IL-2R γ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2R α is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.

Specifications

• Antigen: CD25
• Classification: Monoclonal
• Conjugate: Brilliant Violet 786
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: M-A251
• Description: IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55
• Host Species: Mouse
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.