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CD26 Mouse anti-Rat, Unlabeled, Clone: OX-61, BD

Catalog No. BDB559639 Shop All BD Biosciences Products
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BDB559639 0.1 mg
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Catalog No. BDB559639 Supplier BD Biosciences Supplier No. 559639

Description

Mouse Monoclonal Antibody

The OX-61 antibody reacts with a type II transmembrane glycoprotein, CD26, which is a serine exoprotease identified as dipeptidyl/peptidase IV. Among various biological activities, rat CD26 binds fibronectin and collagen. Rat CD26 is involved in the costimulation of thymocyte proliferation in vitro, particularly the CD4-/CD8- subset, and is developmentally regulated on hematopoietic cells. Although mouse and human CD26 anchor ADA (adenosine deaminase) to cell membranes, rat CD26 does not function as an ADA-binding protein. Rat CD26 is expressed in lung endothelial cells, as well as in various epithelial cells. T cells express lower levels of CD26 than CD4-/CD8- thymocytes. The distribution of CD26 antigen in rat bone marrow cells is similar to that of human CD26. OX-61 monoclonal antibody stains CD4+, CD8+, and Ig+ lymphocytes, and the staining increases upon activation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD26
Applications Flow Cytometry
Classification Monoclonal
Clone OX-61
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Rat dendritic cells enriched from thoracic duct lymph
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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