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CD27 Mouse anti-Human, V450, Clone: M-T271, BD

Catalog No. BDB561408 Shop All BD Biosciences Products
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BDB561408 50 Tests
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Catalog No. BDB561408 Supplier BD Biosciences Supplier No. 561408

Description

Mouse Monoclonal Antibody

The M-T271 monoclonal antibody specifically binds to the human form of CD27, a type I transmembrane, 110 kDa disulfide-linked homodimeric glycoprotein. The CD27 molecule is a lymphocyte-specific member of the TNFR/NGFR family. CD27 is expressed on a subset of human thymocytes and on the majority of mature T lymphocytes. This antibody also crossreacts with a major subset of peripheral blood lymphocytes and monocytes obtained from some non-human primates (NHP) including baboons as well as rhesus and cynomolgus macaques. CD27 expression is detected on the majority of CD3+ lymphocytes and on a subset of CD20+ cells derived from these NHP donors. The CD27 staining patterns on lymphocytes and monocytes from these NHP donors is similar to that observed with peripheral blood lymphocytes from normal human donors.

The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450 nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD27
Applications Flow Cytometry
Classification Monoclonal
Clone M-T271
Conjugate Violet Fluor 450 (V450)
Description TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human T-CLL cells
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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