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CD275 Mouse anti-Human, PE, Clone: 2D3/B7-H2, BD

Catalog No. BDB552502 Shop All BD Biosciences Products
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BDB552502 100 Tests
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Catalog No. BDB552502 Supplier BD Biosciences Supplier No. 552502

Description

Mouse Monoclonal Antibody

The 2D3 monoclonal antibody specifically binds to CD275, which is also known as B7 homolog 2 (B7-H2/B7H2) and B7-related protein 1 (B7RP-1). CD275 is a type I transmembrane glycoprotein that belongs to the Ig superfamily. CD275 is likewise known as Inducible T-cell co-stimulator ligand (ICOS Ligand /ICOSLG/ICOS-L). It can bind to CD278 (ICOS) and costimulate the proliferation and cytokine production of antigen-stimulated human T cells. CD275 is variable expressed by subsets of B cells, monocytes, macrophages, dendritic cells and endothelial cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD275
Applications Flow Cytometry
Classification Monoclonal
Clone 2D3/B7-H2
Conjugate PE
Description ICOSLG; ICOS ligand; LICOS; B7-H2; B7 homolog 2; B7RP-1; GL50
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human B7-H2
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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For Research Use Only.

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