CD28 Mouse anti-Human, PerCP-Cy5.5, Clone: L293, BD

Catalog No.	Quantity
BDB337181	50 Tests

Catalog No. BDB337181 Supplier BD Biosciences Supplier No. 337181

Description

Mouse Monoclonal Antibody

The CD28 antibody, clone L293,22 is derived from hybridization of Sp2/0-Ag14 mouse myeloma cells with spleen cells from BALB/c mice immunized with the HPB-ALL T-cell line.

The CD28 antigen, a disulfide-linked homodimeric glycoprotein, Mr 44 kilodaltons (kd), is a cell-adhesion molecule (CAM) and functions as the ligand for CD80 (B7-1) and CD86 (B7-2) antigens, which are present on activated B lymphocytes, monocytes, and dendritic cells. Interaction of the CD28 antigen with CD80 or CD86 antigens, or both, co-stimulates CD2 and CD3 antigen/T-cell antigen receptor (TCR)–dependent T-cell–mediated proliferation and cytotoxicity.

Specifications

• Antigen: CD28
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: L293
• Concentration: 6μg/mL
• Conjugate: PerCP-Cyanine5.5
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Host Species: Mouse
• Immunogen: HPB-ALL T-cell line
• Purification Method: Affinity Purified
• Quantity: 50 Tests
• Regulatory Status: RUO
• Research Discipline: Immunology
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.