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CD29 Mouse anti-Pig, Alexa Fluor 647, Clone: NaM160-1A3, BD

Catalog No. BDB561496 Shop All BD Biosciences Products
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BDB561496 50 μg
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Catalog No. BDB561496 Supplier BD Biosciences Supplier No. 561496
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Description

Mouse Monoclonal Antibody

The NaM160-1A3 monoclonal antibody specifically binds to the 116-kDa integrin β 1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin α chains. With α 1 through α 6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with α v (CD51), it forms α v β 1 integrin. As a result, CD29 has a broad tissue distribution, including leukocytes, endothelia, epithelia, and oocytes. Porcine CD29 is believed to be a major target for natural antibodies involved in rejection of pig-to-human xenografts, and a mAb to block recognition of pig CD29 may have therapeutic applications. NaM160-1A3 mAb does not crossreact with human peripheral blood lymphocytes or umbilical cord vein endothelial cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD29
Applications Flow Cytometry
Classification Monoclonal
Clone NaM160-1A3
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Description Integrin β1 chain
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Pig platelets
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Pig
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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