CD29 Rat anti-Mouse, Unlabeled, Clone: 9EG7, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 550531

Catalog No. BDB550531

Description

The 9EG7 antibody reacts with the 130kDa integrin β1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin αchains. With α1 through α6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with αv (CD51), it forms αvβ1 integrin. It also associates with the integrin α7 α8 and α9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, and epithelia. 9EG7 mAb has been shown to inhibit both the α6β1 mediated binding of lymphocytes to endothelial cells and the adhesion mediated by activated, but not unactivated, α4β1-integrin. The source of the immunogen was mouse lymph node-derived endothelial cell line TME.

Specifications

• Antigen: CD29
• Classification: Monoclonal
• Concentration: 31.25μg/mL
• Description: Integrin β1 chain
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: 9EG7
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
• Immunogen: Mouse endothelial cell line
• Quantity: 1 mL
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.