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CD29 Rat anti-Mouse, Unlabeled, Clone: 9EG7, BD

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Description

Rat Monoclonal Antibody

The 9EG7 antibody reacts with the 130kDa integrin β1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin αchains. With α1 through α6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with αv (CD51), it forms αvβ1 integrin. It also associates with the integrin α7 α8 and α9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, and epithelia. 9EG7 mAb has been shown to inhibit both the α6β1 mediated binding of lymphocytes to endothelial cells and the adhesion mediated by activated, but not unactivated, α4β1-integrin. The source of the immunogen was mouse lymph node-derived endothelial cell line TME.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD29
Applications Flow Cytometry
Classification Monoclonal
Clone 9EG7
Concentration 31.25μg/mL
Conjugate Unconjugated
Description Integrin β1 chain
Formulation Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse endothelial cell line
Purification Method Affinity Purified
Quantity 1 mL
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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