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Description
CD3 reacts with ε chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex is composed of at least six proteins that range in molecular weight from 20 to 30kDa. The antigen recognized by CD3 antibodies is noncovalently associated with either α/β or γ/δ TCR (70 to 90kDa). The CD3 antigen is present on 61% to 85% of normal peripheral blood lymphocytes 60% to 85% of thymocytes and on Purkinje cells in cerebellum. This antibody has a Mitogenic effect on most peripheral blood T lymphocytes, provided appropriate functional monocytes are present.
Host Species: Mouse
Clone: SK7
Isotype: IgG1 κ
Species Reactivity: Human
Flow Cytometry
Specifications
Specifications
| Antigen | CD3 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | SK7 |
| Conjugate | APC-H7 |
| Description | CD3-epsilon; CD3E; Leu4; T-cell surface antigen T3/Leu-4 epsilon chain; T3E |
| Formulation | Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human Thymocytes |
| Purification Method | Affinity Purified |
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For Research Use Only.
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