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CD3/CD4 Mouse anti-Human, FITC, PE, Invitrogen™

Antibody Cocktail

Manufacturer:  Invitrogen MA112264

Catalog No. 01-670-959


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Description

Description

This antibody is a monoclonal mixture of FITC-conjugated CD3 (clone M2AB, isotype IgG1) and PE-conjugated CD4 (clone 7E14, isotype IgG1).

T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
Specifications

Specifications

CD3/CD4
Cocktail
FITC, PE
CD3D
Liquid
CD3D, CD3E, CD3G, CD4
human thymocytes and human peripheral blood T lymphocytes
Protein A/G
RUO
Antibody
915, 916, 917, 920
Flow Cytometry
M2AB, 7E14
PBS with 0.2% carrier protein and 0.08% sodium azide
P01730, P04234, P07766, P09693
CD3e, CD3 epsilon, FLJ18683, T3E, TCRE, CD3-epsilon, CD3e antigen, epsilon polypeptide TiT3 complex, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Mouse
IgG1
50 Tests
4° C, do not freeze
Primary
Human
Documents
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