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CD3 Mouse anti-Human, Brilliant Violet 605, Clone: SK7, BD

Mouse Monoclonal Antibody

$201.00 - $406.00

Specifications

Antigen CD3
Isotype IgG1, κ
Immunogen Human Thymocytes
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Conjugate Brilliant Violet 605
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB563217
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BD Biosciences
563217
25 Tests
Each for $201.00
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BDB563219
View Documents
BD Biosciences
563219
100 Tests
Each for $406.00
Add to cart
 
Description

Description

The SK7 (Leu-4) monoclonal antibody specifically binds to the epsilon chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex is composed of at least six proteins that range in molecular weight from 20 to 30 kDa. The antigen recognized by CD3 antibodies is noncovalently associated with either α / β or γ/ δ TCR (70 to 90 kDa). The CD3 antigen is present on 61% to 85% of normal peripheral blood lymphocytes 60% to 85% of thymocytes and on Purkinje cells in cerebellum. The soluble form of this antibody has a mitogenic effect on most peripheral blood T lymphocytes, provided appropriate functional monocytes are present.

This antibody is conjugated to BD Horizon BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max of 602-nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20-nm filter set. BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605-nm. Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers. BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser.

Specifications

Specifications

CD3
Human Thymocytes
Brilliant Violet 605
Flow Cytometry
RUO
SK7
CD3-epsilon; CD3E; Leu4; T-cell surface antigen T3/Leu-4 epsilon chain; T3E
IgG1, κ
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Mouse
Affinity Purified
Monoclonal
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
SDS
Product Certifications

For Research Use Only.

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