Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD3 Mouse anti-Human, Brilliant Violet 510, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 563109

Catalog No. BDB563109


Only null left
Add to Cart

Description

Description

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon™ BV510 can be excited by the violet laser and detected in the BD Horizon™ V500 (525/50-nm) filter set. BD Horizon™ BV510 conjugates are useful for the detection of dim markers off the violet laser.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD3
Monoclonal
Brilliant Violet 510
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
50 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
UCHT1
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.