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CD3 Mouse anti-Human, PE-Cy7, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563423

Catalog No. BDB563423


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Description

Description

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Specifications

Specifications

CD3
UCHT1
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Affinity Purified
Human infant thymocytes and peripheral blood lymphocytes from a Sezary
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE-Cyanine7
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Primary
Human
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