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CD3 Mouse anti-Rat, PE, Clone: G4.18, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 554833
Description
The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and dendritic epidermal T cells. It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target cells. In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance. Pre-incubation of splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 (Cat. No. 556970), blocks staining with mAb G4.18.

Specifications
CD3 | |
Monoclonal | |
0.2mg/mL | |
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
PHA-stimulated rat lymph node and spleen cells | |
0.2 mg | |
Immunology | |
Rat | |
IgG3 κ |
Flow Cytometry | |
G4.18 | |
PE | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Safety and Handling
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For Research Use Only.