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CD3 Mouse anti-Human, V450, Clone: UCHT1, BD

Catalog No. BDB560366 Shop All BD Biosciences Products
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BDB560365 120 Tests
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Catalog No. BDB560366 Supplier BD Biosciences Supplier No. 560366
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Description

Mouse Monoclonal Antibody

Reacts with the human ε-chain, a 20kDa subunit of CD3/T cell antigen receptor complex found on 70%-80% of normal human peripheral blood lymphocytes and 60%-85% of thymocytes. Studies from the HLDA Workshop show this antibody to be mitogenic when used in conjunction with pokeweed mitogen. CD3 plays a role in signal transduction during antigen recognition. UCHT1 antibody stains intracellular CD3 unlike the other CD3 clone, HIT3a, which stains only the extracellular CD3. The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

Host Species: Mouse
Clone: UCHT1
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry, Functional Assay

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3
Applications Flow Cytometry
Classification Monoclonal
Clone UCHT1
Conjugate Violet Fluor 450 (V450)
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Purification Method Affinity Purified
Quantity 30 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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