CD309 (VEGFR-2) Mouse anti-Human, Alexa Fluor 647, Clone: 89106, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560495

Catalog No. BDB560495

Description

The 89106 monoclonal antibody reacts with CD309 (vascular endothelial growth factor receptor-2 (VEGFR-2)), a receptor protein tyrosine kinase closely related to CD117 (c-kit) and CD140a (PDGF Receptor α chain) of the immunoglobulin superfamily. VEGFR-2, also known as fetal liver kinase 1 (Flk-1) or kinase insert domain receptor (KDR), is a receptor for vascular endothelial growth factor (VEGF). It is expressed, at the mRNA and protein levels, on distinct sets of mesoderm during gastrulation and on endothelial cells in embryonic tissues. In vivoin vitro studies indicate that VEGFR-2 is required for the embryonic development of vascular endothelial and hematopoietic cells. Human cardiac progenitor cells derived from human embryonic stem cells arise from a population of cells that express VEGFR-2.

Specifications

• Antigen: CD309
• Classification: Monoclonal
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human VEGFR-2
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: 89106
• Description: FLK1; Fetal liver kinase 1; KDR; VEGFR2; VEGF Receptor 2
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov