CD153 Mouse anti-Human, Clone: 116614, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523859
In direct ELISAs, no cross-reactivity with recombit human (rh) CD27 Ligand, recombit mouse CD30 Ligand, or rhCD40 Ligand is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin ft.s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin ft.s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin ft.s lymphomas (including Burkitt ft.s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
|PBS with 5% trehalose and No Preservative|
|Tumor necrosis factor ligand superfamily member 8, CD30 ligand, CD30-L, CD153, TNFSF8, CD30L, CD30LG|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Neutralization|
|Mouse myeloma cell line NS0-derived recombit human CD30 Ligand/TNFSF8 Gln63-Asp234|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok