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CD31 Mouse anti-Human, Alexa Fluor 488, Clone: M89D3, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 558068

Catalog No. BDB558068


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Description

Description

Reacts with CD31, also known as platelet endothelial cell adhesion molecule - 1 (PECAM-1), a sigle chain, type I transmembrane protein of approximately 130 - 140 kDa. CD31 is a member of the immunoglobulin supergene family, its extracellular region is composed of 574 aminoacids and contains six C2-type Ig domains, its intracellular region is composed of 118 residues. CD31 (PECAM-1) is expressed on endothelial cells, platelets, monocytes, neutrophils and NK cells. It has also been observed on subsets of T cells, but not on circulating B cells. It has been implicated in a number of cellular phenomena, including vascular wound healing, angiogenesis, and transendothelial migration of leukocytes and platelet aggregation in inflammatory responses.

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