CD31 Mouse anti-Human, Brilliant Violet 421, Clone: WM59, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 564089

Catalog No. BDB564089

Description

The WM59 monoclonal antibody specifically binds to a 130 kDa glycoprotein, gpIIa', also known as platelet endothelial cell adhesion molecule-1, (PECAM-1). CD31 has wide tissue distribution and is expressed on platelets, monocytes, granulocytes, and in high amounts on endothelial cells. This molecule has been implicated in a number of cellular phenomena, including vascular wound healing and angiogenesis, and transendothelial migration of leukocytes in inflammatory responses.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.

Specifications

• Antigen: CD31
• Classification: Monoclonal
• Conjugate: Brilliant Violet 421
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: WM59
• Description: EndoCAM; GPIIA'; PECA1; PECAM1; Platelet endothelial cell adhesion molecule
• Host Species: Mouse
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov