CD31 Mouse anti-Human, Brilliant Violet 510, Clone: WM59, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 563454
The WM59 monoclonal antibody specifically binds to a 130 kDa glycoprotein, gpIIa', also known as platelet endothelial cell adhesion molecule-1, (PECAM-1). CD31 has wide tissue distribution and is expressed on platelets, monocytes, granulocytes, and in high amounts on endothelial cells. This molecule has been implicated in a number of cellular phenomena, including vascular wound healing and angiogenesis, and transendothelial migration of leukocytes in inflammatory responses.
The antibody was conjugated to BD Horizon BV510 which is part of the BD Horizon Brilliant Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.
|EndoCAM; GPIIA'; PECA1; PECAM1; Platelet endothelial cell adhesion molecule|
|Brilliant Violet 510|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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