CD31 (PECAM-1) Mouse anti-Human, PE, Clone: L133.1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 340297

Catalog No. BDB340297

Description

The CD31 (Anti-PECAM-1) antibody recognizes the platelet/endothelial cell adhesion molecule-1 (PECAM-1), a 130 to 140-kilodalton (kDa) single-chain integral membrane glycoprotein that is a member of the immunoglobulin gene superfamily. The CD31 antigen is composed of six extracellular immunoglobulin-like domains belonging to the C2 group. C2 domains are also found in other members of the immunoglobulin superfamily, the cell adhesion molecules (CAMs). The CD31 antigen functions as a vascular cell adhesion molecule and is involved in the process of leucocyte migration through the intercellular junctions of vascular endothelial cells. It may also be involved in thrombosis, angiogenesis, wound healing, and inflammation.

Specifications

• Antigen: CD31
• Classification: Monoclonal
• Concentration: 12.5μg/mL
• Description: PECAM-1
• Host Species: Mouse
• Quantity: 50 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: L133.1
• Conjugate: PE
• Formulation: Phosphate buffered saline with gelatin and 0.1% sodium azide.
• Immunogen: Purified human natural killer cells
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store vials at 2-8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.