CD336 Mouse anti-Human, PE, Clone: P44-8.1, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 558563

Catalog No. BDB558563

Description

The p44-8 monoclonal antibody specifically binds to the natural killer (NK) cell receptor, NKp44, which is also known as CD336, Natural cytotoxicity triggering receptor 2 (NCR2), or Lymphocyte antigen 95 homolog (Ly95). NKp44 is a ∽44 kDa type I transmembrane protein that belongs to the natural cytotoxicity receptor (NCR) family within the immunoglobulin superfamily. NKp44 is expressed by activated NK cells. NKp44 serves as an activating receptor that can enhance NK cell mediated lysis of target cells including tumor cells and virus-infected cells. Killer activating receptor associated protein (KARAP), which is also known as DAP12, is an intracellular adaptor protein that can associate with the intracellular region of NKp44. DAP12 can then function to help transmit activating signals through its immunoreceptor tyrosine-based activation motif (ITAM).

Specifications

• Antigen: CD336
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
• Immunogen: Human NKp44 Recombinant Protein
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: P44-8.1
• Description: NCR2; NCTR2; NKp44; NK-p44; LY95; dJ149M18.1; p44-8
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.