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Description
The 563 monoclonal antibody specifically binds to CD34. CD34 is a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting that CD34 may play a role in signal transduction. CD34 may play a role in adhesion of specific antigens to endothelium. Clone 563 belongs to the class III epitope; it is resistant to neuraminidase, chymopapain and glycoprotease. This antibody is able to block the binding of other CD34 mAbs like 581.
Specifications
Specifications
| Antigen | CD34 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 563 |
| Concentration | 0.5mg/mL |
| Conjugate | Unconjugated |
| Description | gp 105-120 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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Safety and Handling
For Research Use Only.
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