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CD34 (gp 105-120) Mouse anti-Human, PE-Cy7, Clone: 581, BD

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Catalog No. BDB560710 Supplier BD Biosciences Supplier No. 560710
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Description

Mouse Monoclonal Antibody

The 581 monoclonal antibody specifically binds to CD34, a sialomucin-like type I transmembrane glycoprotein. This single-chain, 105-120 kDa, heavily O-glycosylated protein is expressed on hematopoietic progenitor cells, vascular endothelium, bone marrow stromal cells and embryonic fibroblasts. The cytoplasmic region of the CD34 antigen is a target for phosphorylation by activated protein kinase C suggesting CD34 may play a role in signal transduction. CD34 may also play a role as an adhesion molecule since it binds to CD62E and CD62L. Clone 581 binds to the class III CD34 epitope, it is resistant to neuraminidase, chymopapain and glycoprotease. The 581 antibody blocks reactivity of another anti-CD34 monoclonal antibody, 8G12.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD34 (gp 105-120)
Applications Flow Cytometry
Classification Monoclonal
Clone 581
Conjugate PE-Cyanine7
Description gp105-120; My10; Hematopoietic progenitor cell antigen CD34
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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