CD344 Mouse anti-Human, Unlabeled, Clone: CH3A4A7, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563657

Catalog No. BDB563657

Description

The CH3A4A7 monoclonal antibody reacts with an extracellular epitope on human CD344 which is also known as Frizzled family receptor 4 (FZD4) or Frizzled-4. CD344 is a member of the Frizzled family of proteins within the G protein-coupled receptor (GPCR) superfamily. CD344 is a receptor for Wnt proteins and participates in the activation of the Wnt/beta-catenin pathway (canonical Wnt signaling). Patients with familial exudative vitreoretinopathy (FEVR) carry mutations in Frizzled-4. This disease is characterized by retinal degeneration and hearing loss. On tissues, CD344 is almost ubiquitously expressed. CD344 is highly expressed in adult heart and skeletal muscle.

Specifications

• Antigen: CD344
• Clone: CH3A4A7
• Description: FZD4; Frizzled family receptor 4; Frizzled-4; Fz-4; FzE4; hFz4; EVR1; FEVR
• Format: Affinity Purified
• Immunogen: Human neuroblastoma Cell Line
• Quantity: 0.1mg
• Storage Requirements: Store undiluted at 4°C
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Murine
• Isotype: IgG₁, κ
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human