Learn More
CD344 Mouse anti-Human, Unlabeled, Clone: CH3A4A7, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 563657
Description
The CH3A4A7 monoclonal antibody reacts with an extracellular epitope on human CD344 which is also known as Frizzled family receptor 4 (FZD4) or Frizzled-4. CD344 is a member of the Frizzled family of proteins within the G protein-coupled receptor (GPCR) superfamily. CD344 is a receptor for Wnt proteins and participates in the activation of the Wnt/beta-catenin pathway (canonical Wnt signaling). Patients with familial exudative vitreoretinopathy (FEVR) carry mutations in Frizzled-4. This disease is characterized by retinal degeneration and hearing loss. On tissues, CD344 is almost ubiquitously expressed. CD344 is highly expressed in adult heart and skeletal muscle.

Specifications
CD344 | |
Monoclonal | |
Unconjugated | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
Flow Cytometry | |
CH3A4A7 | |
FZD4; Frizzled family receptor 4; Frizzled-4; Fz-4; FzE4; hFz4; EVR1; FEVR | |
Human neuroblastoma Cell Line | |
0.1 mg | |
Primary | |
Store undiluted at 4°C |
Your input is important to us. Please complete this form to provide feedback related to the content on this product.