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CD344 Mouse anti-Human, Unlabeled, Clone: CH3A4A7, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 563657

Catalog No. BDB563657


Description

Description

The CH3A4A7 monoclonal antibody reacts with an extracellular epitope on human CD344 which is also known as Frizzled family receptor 4 (FZD4) or Frizzled-4. CD344 is a member of the Frizzled family of proteins within the G protein-coupled receptor (GPCR) superfamily. CD344 is a receptor for Wnt proteins and participates in the activation of the Wnt/beta-catenin pathway (canonical Wnt signaling). Patients with familial exudative vitreoretinopathy (FEVR) carry mutations in Frizzled-4. This disease is characterized by retinal degeneration and hearing loss. On tissues, CD344 is almost ubiquitously expressed. CD344 is highly expressed in adult heart and skeletal muscle.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD344
Monoclonal
Unconjugated
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry
CH3A4A7
FZD4; Frizzled family receptor 4; Frizzled-4; Fz-4; FzE4; hFz4; EVR1; FEVR
Human neuroblastoma Cell Line
0.1 mg
Primary
Store undiluted at 4°C
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