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CD344 Mouse anti-Human, Unlabeled, Clone: CH3A4A7, BD

Catalog No. BDB563657 Shop All BD Biosciences Products
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BDB563657 0.1 mg
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Catalog No. BDB563657 Supplier BD Biosciences Supplier No. 563657

Description

Mouse Monoclonal Antibody

The CH3A4A7 monoclonal antibody reacts with an extracellular epitope on human CD344 which is also known as Frizzled family receptor 4 (FZD4) or Frizzled-4. CD344 is a member of the Frizzled family of proteins within the G protein-coupled receptor (GPCR) superfamily. CD344 is a receptor for Wnt proteins and participates in the activation of the Wnt/beta-catenin pathway (canonical Wnt signaling). Patients with familial exudative vitreoretinopathy (FEVR) carry mutations in Frizzled-4. This disease is characterized by retinal degeneration and hearing loss. On tissues, CD344 is almost ubiquitously expressed. CD344 is highly expressed in adult heart and skeletal muscle.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD344
Applications Flow Cytometry
Classification Monoclonal
Clone CH3A4A7
Conjugate Unconjugated
Description FZD4; Frizzled family receptor 4; Frizzled-4; Fz-4; FzE4; hFz4; EVR1; FEVR
Host Species Mouse
Immunogen Human neuroblastoma Cell Line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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