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  6. anti-CD3zeta/T Cell Receptor zeta Ab-8, Clone: 6B10, Epredia™ LabVision

anti-CD3zeta/T Cell Receptor zeta Ab-8, Clone: 6B10, Epredia™ LabVision

Catalog No. MS1289P0 Shop All Epredia Products
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100 μL
200 μL
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1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS1289P0 100 μL 200μg/mL
MS1289P1 500 μL 200μg/mL
MS1289P 1 mL 200μg/mL
MS1289P1ABX 100 μL 1mg/mL
MS1289PABX 200 μL 1mg/mL
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Catalog No. MS1289P0 Supplier Epredia Supplier No. MS1289P0

Description

Mouse Monoclonal Antibody

CD3 consists of five different polypeptide chains (designated as γ, δ, ε, ζ, and η). The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). It is involved in signal transduction to the T cell interior following antigen recognition, which culminates in cytokine release, cellular proliferation.. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Host Species: Mouse
Clone: 6B10
Isotype: IgG1
Cross Reactivity: Human, Mouse, and Rat. Others-not tested.
Epitope: aa 36-54 of T Cell Receptor zeta Chain
Immunogen: Synthetic peptide corresponding to aa 36-54 of T Cell Receptor ζ Chain.
Molecular Weight: ∽20kDa
Positive Control: Jurkat cells.
Cellular Localization: Cell membrane

Ab-8 reacts with phosphorylated and unphosphorylated forms of of T Cell Receptor zeta Chain. It co-immunoprecipitates the zeta chain associated tyrosine kinase ZAP-70

Immunoprecipitation, Western Blotting

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Antigen CD3ζ/T Cell Receptor ζ Ab-8
Classification Monoclonal
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Synthetic peptide corresponding to aa 36-54 of T Cell Receptor ζ Chain.
Purification Method Jurkat cells
Quantity 100 μL
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Content And Storage 2–8 degrees
Form Purified
Isotype IgG1
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